Developmental Cell Growth

PAX: developmental control genes in cell growth and differentiation.

Embryonic development requires the generation of undifferentiated cells and their subsequent maturation into differentiated cells with a specific function. The molecular events that determine the identity of differentiated cells are evidently complex and, despite encouraging results, remain largely unknown. The development of individual undifferentiated cells into their mature differentiated ph...

Blood Cell Growth Factors

  SUMMARY Growth factors or colony stimulating factors (CSFs)recently became the subject of headlines around the world. Many published articles in the last few years indicate that the CSFs can correct anemia and pancytopenia of the great majority of patients. Recombinant CSFs are available to the many scientific and therapeutic centers in the U.S.A, Europe and Japan these days. Erythrop oieti...

Fetal growth and developmental programming.

The environment in utero and in early neonatal life may induce a permanent response in the fetus and the newborn, leading to enhanced susceptibility to later diseases. This review concentrates on the role and mechanisms of events during the antenatal and immediate postnatal period resulting in later life diseases, concentrating on abnormal growth patterns of the fetus. Fetal overgrowth is relat...

Developmental Biology: Micromanaging Muscle Growth

Much remains to be learnt about the in vivo function of specific microRNAs. Recently, the conserved microRNA miR-1 has been found to be essential for Drosophila development. miR-1 mutants die during the rapid larval growth phase with severe muscle defects.

Brain Evolution: Developmental Constraints and Relative Developmental Growth